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. 2021 Jul 13;11:709070. doi: 10.3389/fonc.2021.709070

Table 3.

The pooled sensitivity, specificity, PLR, and NLR with corresponding 95% CIs for each included study under different morphological standards.

Index test SEN (95% CI) SPE (95% CI) DOR (95% CI) PLR (95% CI) NLR (95% CI) AUC
Total 0.73 (0.68-0.77) 0.74 (0.68-0.80) 7.85 (5.78-10.66) 2.85 (2.27-3.58) 0.36 (0.31-0.42) 0.79 (0.76-0.83)
5MM 0.75 (0.67-0.81) 0.64 (0.57-0.71) 5.20 (3.76-7.18) 2.07 (1.76-2.43) 0.40 (0.31-0.50) 0.75 (0.71-0.78)
MS 0.74 (0.67-0.80) 0.79 (0.58-0.91) 10.86 (4.19-28.13) 3.57 (1.65-7.74) 0.33 (0.25-0.43) 0.77 (0.73-0.81)
5MM+MS 0.81 (0.74-0.87) 0.67 (0.58-0.74) 8.53 (5.59-13.01) 2.42 (1.94-3.03) 0.28 (0.21-0.39) 0.81 (0.78-0.85)
8MM+MS 0.72 (0.60-0.82) 0.66 (0.47-0.81) 5.18 (1.60-16.80) 2.15 (1.16-3.99) 0.42 (0.23-0.75) 0.76 (0.72-0.79)
10MM+MS 0.62 (0.34-0.83) 0.91 (0.51-0.99) 16.21 (3.74-70.21) 6.80 (1.22-37.81) 0.42 (0.24-0.72) 0.81 (0.77-0.84)

MS, morphological standards; DOR, diagnostic odds ratio; PLR, positive likelihood ratio; NLR, negative likelihood ratio; AUC, area under the curve.