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. 2021 Jul 13;11(16):8112–8128. doi: 10.7150/thno.54961

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CCDC65 suppresses gastric cancer metastasis in vitro and in vivo. (A-D) Transwell assay, boyden assay and (E) wound-healing assays evaluated the migration and invasion of gastric cancer cells treated with CCDC65 plasmid, si-CCDC65, CCDC65 lentivirus and corresponding control group. (F) A pulmonary metastasis model was adopted to evaluate the effect of CCDC65 on metastasis (n = 5). (G) Representative H&E as well as IHC staining of pulmonary metastatic nodules are shown. Scale bar, 50 μm.