Table 4.
List of identified ongoing trials to extract radiomic features. Only aims concerning radiomics are mentioned above. In the second column # are the number of patients enrolled retrospectively (R) or prospectively (P). The third column displays the imaging modality (mpMRI=multiparametric magnetic resonance imaging, PSMA/FDG-PET=prostate specific membrane antigen fluorodeoxyglucose positron emission tomography, CT=computer tomography). The fourth column gives an overview of the study's aim(s).
| Study | # | Imaging Modality | Aim(s) |
|---|---|---|---|
| NCT03979573 | 90 (P) | mpMRI | Identification and monitoring of patients with RF in combination with clinical and molecular markers during active surveillance of PCa to reduce discontinuation. |
| NCT02242773 | 207 (P) | mpMRI | Correlation of RF with progression during active surveillance and with genomic signatures and other biomarkers. |
| NCT03180398 | 20 (P) | mpMRI | Extracted RF are used to identify dominant lesions within the prostate. These RF are monitored longitudinally to analyze their correlation with the local control. |
| NCT04219059 | 200 (R) | mpMRI | Evaluates if RF on primitive prostate lesions can describe histological characteristics, lymph node involvement and disease extension. |
| NCT04343885 | 140 (P) | PSMA/FDG-PET, CT, bone scans | Prognostic and predictive value RF from PET, CT or bone scans after Lutetium-177 PSMA radionuclide treatment and/ or chemotherapy. |