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. 2021 Jul 6;11(16):7911–7947. doi: 10.7150/thno.56639

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This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

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Summary of targeted radionuclide therapy of glioblastoma. Main consideration for the development of new radiopharmaceuticals for brain tumours, comparing three different radiolabelled vectors (small molecules, peptides and monoclonal antibodies (mAbs). Abbreviations and footnoted contents: Auger electron (AE), blood-brain barrier (BBB), convection-enhanced delivery (CED), cell-penetrating peptides (CPP), intravenous (IV), organs at risk (OAR), reticulo-endothelial system (RES), receptor-mediated transport (RMT), specific activity (SA), targeted radionuclide therapy (TRT), carrier-mediated transport (CMT), half-life (T1/2).