Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Strategies to enhance blood-brain barrier (BBB) penetration. (1) harnessing the homing ability of certain stem cells, (2) low affinity to efflux pumps or co-administration with inhibitors of efflux pumps, (3) targeted irradiation, (4) a combination of low-intensity focused ultrasound (FUS) pulses and circulating microbubbles, (5) infusion of hypertonic solutions, such as mannitol or vasodilatator and bradykinin analog RMP-7 and (6) nanoparticle-mediated delivery systems 118.
