Table 2.
Shortlisted antimicrobial peptides and their Ramachandran Plot statistics
| Peptide | APD3 ID | Definition | WWIHS | NET CHARGE | iHHM | Residues in most favoured regions (%) | Residues in additional allowed regions (%) | Residues in generously allowed regions (%) |
|---|---|---|---|---|---|---|---|---|
| ALWMTLLKKVLKAAAKAALNAVLVGANA | AP00160 | Dermaseptin-S4 | 0.92 | 4 | 4.71 | 63.6 | 27.3 | 9.1 |
| GWFKKAWRKVKNAGRRVLKGVGIHYGVGLI | AP00692 | Hagfish cathelicidin | 0.24 | 8 | 6.41 | 61.9 | 28.6 | 9.5 |
| KIPCGESCVWIPCVTSIFNCKCKENKVCYHD | AP01061 | Circulin D | 1.27 | 1 | 5.43 | 63.6 | 27.3 | 9.1 |
| ATCYCRTGRCATRESLSGVCEISGRLYRLCCR | AP00180 | Human defensin 5 | 1.39 | 4 | 3.83 | 92.9 | 7.1 | 0.0 |
| VTCYCRRTRCGFRERLSGACGYRGRIYRLCCR | AP00222 | RatNP-1 rat defensin | 1.02 | 8 | 4.29 | 90.4 | 9.6 | 0.0 |
| VTCYCRSTRCGFRERLSGACGYRGRIYRLCCR | AP00223 | RatNP-2 rat defensin | 1.7 | 7 | 4.01 | 90.0 | 10.0 | 0.0 |
| DFASCHTNGGICLPNRCPGHMIQIGICFRPRVKCCRSW | AP00036 | Bovine beta-defensin 1 | 0.22 | 4 | 4.72 | 80.8 | 11.5 | 3.8 |
| GFGCNGPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY | AP00549 | Plectasin | 2.11 | 1 | 3.67 | 76.7 | 23.3 | 0.0 |
| FFLLFLQGAAGNSVLCRIRGGRCHVGSCHFPERHIGRCSGFQACCIRTWG | AP02148 | Apl-AvBD16 | 3.26 | 5 | 5.26 | 75.9 | 24.1 | 0.0 |
| LFGSVKAWFKGAKKGFQDYRYQKDMAKMNKRYGPNWQQRGGQEPPADAQANDQPP | AP02733 | Piscidin 6 | 2.93 | 5 | 6.41 | 89.3 | 3.6 | 3.6 |