Table 3.
Associations between significant SNPs and GDM related biomedical indexes stratified by disease status.
| Status | Biomedical Indexes (Mean ± SD) | SNP | Gene | β | t-statistics | P |
|---|---|---|---|---|---|---|
| Patients with GDM (N=1,282) | Fasting Glucose (6.9 ± 0.9) | rs80196932 | NUS1 | 0.03 | 0.50 | 0.6182 |
| rs117267808 | GP2 | 0.22 | 3.36 | 0.0008 | ||
| HbA1c (7.3 ± 0.5) | rs80196932 | NUS1 | -0.11 | -3.34 | 0.0009 | |
| rs117267808 | GP2 | 0.02 | 0.58 | 0.5630 | ||
| Controls (N=2,968) | Fasting Glucose (4.6 ± 0.2) | rs80196932 | NUS1 | -0.01 | -0.87 | 0.3820 |
| rs117267808 | GP2 | 0.04 | 3.38 | 0.0007 | ||
| HbA1c (5.2 ± 0.5) | rs80196932 | NUS1 | -0.07 | -3.66 | 0.0003 | |
| rs117267808 | GP2 | -0.02 | -0.78 | 0.4375 |