Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 13;12:651645. doi: 10.3389/fphys.2021.651645

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Li, Liu, Lu, Dai, Chen and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Di-tert-butyl dicarbonate (BOC-2) treatment could deteriorate renal function and pathological injury after ischemic injury in non-diabetic (ND) mice. Male C57BL/6J mice were subjected to sham operation or 30 min of bilateral renal ischemia followed by 48 h of reperfusion (I/R48). For the BOC-2 group, BOC-2 was given at a dose of 5 μg/kg intraperitoneally 30 min before renal ischemia–reperfusion. (A,B) Serum creatinine and blood urea nitrogen (BUN). (C) Hematoxylin and eosin (HE) staining for renal tissues. Scale bar, 100 μm. (D) TUNEL assay to reveal apoptosis of renal tissues. Scale bar, 50 μm. (E) Semi-quantification for renal tissue damage. (F) Statistical analysis for TUNEL-positive cells. All the data are shown as the mean ± SD (n = 6). *p < 0.05 vs. the relevant ND + I/R group.