Table 4.
Multivariable logistic regression analysis of ART characteristics on birth defects among ART-conceived births.
| Characteristics | Levels | No. of birth | No. of birth defects (%) | aRR (95%CI) | P value |
|---|---|---|---|---|---|
| Maternal age, year | – | 1552 | 217 (14•0) | 1•01 (0•96–1•05) | 0•776 |
| Parity | Nulliparous | 1394 | 194 (13•9) | 1•00 | |
| Multiparous | 158 | 23 (14•6) | 1•03 (0•59–1•80) | 0•907 | |
| Maternal pre-pregnancy BMI, kg/m2 | – | 1552 | 217 (14•0) | 0•99 (0•94–1•04) | 0•764 |
| Diabetes | No | 1062 | 153 (14•4) | 1•00 | |
| Yes | 435 | 62 (14•3) | 0•97 (0•67–1•39) | 0•850 | |
| Hypertension | No | 1322 | 187 (14•1) | 1•00 | |
| Yes | 170 | 27 (15•9) | 1•07 (0•65–1•76) | 0•804 | |
| Ovarian dysfunction | No | 1404 | 189 (13•5) | 1•00 | |
| Yes | 148 | 28 (18•9) | 1•22 (0•66–2•25) | 0•528 | |
| Regimen of ovulation induction | GnRH-a | 712 | 80 (11•2) | 1•00 | |
| GnRHant | 750 | 119 (15•9) | 1•47 (1•04–2•07) | 0•029 | |
| Microstimulation | 90 | 18 (20•0) | 1•85 (0•86–3•99) | 0•117 |