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. 2020 Sep 9;3:100085. doi: 10.1016/j.ajpc.2020.100085

Table 5.

Long-term consequences of strokes in young adults.

Consequence Description
Physical
 Functional disability
  • Main determinant of independence or the need for care-givers, 20–30% reported moderate to severe functional impairment [86].

 Pain Syndromes
  • Includes headache, central post stroke pain (CPSP), complex regional pain syndrome, and pain associated with spasticity and shoulder subluxation.

  • Data is scarce on the prevalence, especially among the young and for each subtype. CPSP is reported to be present in 6% of young adults with stroke [87,88].

  • Headache is reported in 15%–20% [86]

 Epilepsy
  • Prevalence is up to 12% of young adults [89].

Psychosocial
 Cognitive impairment
  • Present in up to 40% of young adults on long term follow up [90]

 Depression
  • Between 17 and 29% of young stroke patients develop depressive symptoms [91,92]

  • Associated with poor functional outcome and increased risk of suicide [93]

 Anxiety
  • Between 19 and 23% of young stroke patients develop anxiety [91,92]

 Fatigue
  • 41% of young adults with stroke experienced symptoms of fatigue, compared to 18% in controls.

  • Is associated with a poor functional outcome [94]

 Sexual Dysfunction
  • One study reported that up to one third of young stroke patients develop sexual dysfunction, however, it is believed that depression and the use of ACE inhibitors confounds to it [95].

 Return to work
  • Between 50% and 70% of young adults with stroke return to work, 25% of whom need adjustments to previous duties.

  • On average, it takes 8 months for patients to return to work [86]

  • 20% of the patients who had returned to work at 1 year were not working at 5 years after ischemic stroke

  • Hemorrhagic strokes, large anterior strokes, strokes caused by large artery atherosclerosis, and cardioembolism pose higher risk for not to return to work [96].