Table 10c.
Make Early Diagnosis to Prevent Early Dealths (MEDPED) diagnostic criteria for Heterozygous Familial Hypercholesterolemia [181,182].
| Familial Hypercholesterolemia (FH) is diagnosed if total cholesterol exceeds these cutpoints in mg/dL (mmol/L)∗ | ||||
|---|---|---|---|---|
| Age (years) | First degree relative with FH | Second degree relative with FH | Third degree relative with FH | General population |
| <20 | 220 (5.7) | 230 (5.9) | 240 (6.2) | 270 (7.0) |
| 20–29 | 240 (6.2) | 250 (6.5) | 260 (6.7) | 290 (7.5) |
| 30–39 | 270 (7.0) | 280 (7.2) | 290 (7.5) | 340 (8.8) |
| ≥ 40 | 290 (7.5) | 300 (7.8) | 310 (8.0) | 360 (9.3) |
∗
The total cholesterol cutpoints for FH is dependent upon the confirmed cases of FH in the family. If FH is not diagnosed in the family, then the cutpoint for diagnosis is as per general population.