Table 1.
Demographics and medications at baseline. Results expressed as mean ± SD or percentage.
| Parameter | No Risk Factors n = 165 | Risk Factors n = 492 | p-value |
|---|---|---|---|
| Age, years | 55.7 ± 9.4 | 55.7 ± 9.4 | 0.99 |
| Female, % | 17.0 | 16.5 | 0.88 |
| Caucasian, % | 96.4 | 93.3 | 0.15 |
| Current Smoker | 0 | 31.0 | <0.001 |
| BMI, kg/m2 | 28.6 ± 4.7 | 30.6 ± 5.7 | <0.001 |
| Hypertension, % | 0 | 81.7 | <0.001 |
| Diabetes, % | 0 | 28.5 | <0.001 |
| Hyperlipidemia, % | 0 | 77.8 | <0.001 |
| Angina, % | 31.5 | 45.7 | 0.002 |
| History of CHF, % | 0.6 | 3.9 | 0.035 |
| History of MI, % | 34.5 | 30.9 | 0.38 |
| History of stroke, % | 0 | 2.2 | 0.07 |
| History of PCI, % | 21.8 | 36.4 | 0.001 |
| History of CABG, % | 1.8 | 1.9 | 1.0 |
| Medication use prior to study entry | |||
| Aspirin, % | 94.5 | 91.7 | 0.23 |
| Statins, % | 74.5 | 77.4 | 0.45 |
| Beta Blockers, % | 61.8 | 74.6 | 0.002 |
| ACE Inhibitors, % | 29.7 | 51.8 | <0.001 |
| Medication use during studies | |||
| Aspirin, % | 96.4 | 92.1 | 0.06 |
| Statins, % | 93.9 | 94.5 | 0.78 |
| Beta Blockers, % | 57.6 | 76.6 | <0.001 |
| ACE Inhibitors, % | 34.5 | 55.7 | <0.001 |
ACE inhibitors = Angiotensin converting enzyme inhibitors, CHF = Congestive heart failure, CABG = Coronary artery bypass graft, MI = Myocardial infarction, PCI = percutaneous coronary intervention, SD = standard deviation.