Table 1. Baseline clinical characteristics of the patients.
| Characteristics | All Patients (n = 83) |
|---|---|
| Age, years | 68.1 ± 10.5 |
| Male, n (%) | 54 (65.1) |
| Ever smokers, n (%) | 50 (60.2) |
| Height, cm | 162.3 ± 8.5 |
| Weight, kg | 64.7 ± 10.9 |
| BMI, kg/m2 | 24.5 ± 3.4 |
| Home O2, n (%) | 5 (6.0) |
| Interstitial lung disease | |
| IPF, n (%) | 57 (68.7) |
| CTD, n (%) | 12 (14.5) |
| COP, n (%) | 8 (9.6) |
| NSIP, n (%) | 5 (6.0) |
| HP, n (%) | 1 (1.2) |
| Radiologic pattern | |
| UIP, n (%) | 56 (67.4) |
| NSIP, n (%) | 10 (12.1) |
| OP, n (%) | 10 (12.1) |
| Indeterminate, n (%) | 6 (7.2) |
| Pulmonary function | |
| FVC, % predicted | 73.9 ± 15.6 |
| DLco, % predicted | 59.1 ± 17.0 |
| TLC, % predicted | 72.5 ± 12.4 |
| FEV1/FVC, % | 77.0 ± 8.5 |
| Six-minute walk test | |
| Distance, m | 402.2 ± 99.0 |
| Baseline SpO2, % | 95.9 ± 2.5 |
| Lowest SpO2, % | 90.6 ± 5.9 |
| BAL | |
| Total WBC count, cell/μL | 2,135.7 ± 3,402.5 |
| Neutrophil, % | 28.6 ± 26.3 |
| Lymphocyte, % | 18.6 ± 21.8 |
| PaO2, mmHg | 88.0 ± 28.2 |
| BNP, pg/mL | 421.1 ± 734.5 |
| Baseline IL-6, pg/mL | 14.9 ± 33.8 |
| CRP, mg/dL | 2.5 ± 5.5 |
| WBC, cell/μL | 8,094.8 ± 3,041.7 |
| LDH, IU/L | 264.8 ± 86.3 |
Values are presented as mean ± standard deviation or number (%).
BMI, body mass index; IPF, idiopathic pulmonary fibrosis; CTD, connective tissue disease-associated interstitial lung disease; COP, cryptogenic organizing pneumonia; NSIP, non-specific interstitial pneumonia; HP, hypersensitivity pneumonitis; UIP, usual interstitial pneumonia; OP, organizing pneumonia; FVC, forced vital capacity; DLco, diffusing capacity of the lungs for carbon monoxide; TLC, total lung capacity; SpO2, saturation of peripheral oxygen; BAL, bronchoalveolar lavage; WBC, white blood cell; PaO2, partial pressure of oxygen; BNP, brain natriuretic peptide; IL-6, interleukin-6; CRP, C-reactive protein; LDH, lactate dehydrogenase.