Table 7.

Association between lymph volume change (LV%) and the symptom classes at 12 months post-surgery

Median (IQR) LV%	Low symptom class	Moderate symptom class	Severe symptom class	p value
Pre-surgery	− 1% (− 3–1%)	0% (− 2–2%)	− 1%*** (− 5–2%)	0.148
8 weeks post-surgery	− 1% (− 3–3%)	1% (− 2–4%)	3%*** (− 2–7%)	0.041
12 months post-surgery	− 1% (− 3–3%)	1% (− 2–5%)	6%*** (− 1–9%)	0.001; A < C

A (low), B (moderate), and C (severe) symptom class pairwise differences between the three classes with a Bonferroni correction at the 5% alpha level

^*p < 0.05

^**p <0.01

^***p < 0.001 – repeated measures ANOVA over the three time points