. 2017 Sep 26;88(1):100–106. doi: 10.2319/031217-185.1

Table 1.

Data on the Studies Included in the Review

Author(s), Year	Design	Sample Size	Age, Y	Alignment Efficiency
Cobb et al., 1998	Randomized clinical trial	G. 0.018 inch: 85 arches	Not assessed	One-month difference in favor of 0.022-inch bracket slot in mandibular arch (P < .05)
Cobb et al., 1998	Randomized clinical trial	G. 0.022 inch: 70 arches	Not assessed
Amditis and Smith, 2000	Retrospective clinical trial	G. 0.018 inch: 32 patients	G. 0.018 inch: 15.6	Not assessed
Amditis and Smith, 2000	Retrospective clinical trial	G. 0.022 inch: 32 patients	G. 0.022 inch: 14.9	Not assessed
Vu et al., 2008	Retrospective clinical trial	G. 0.018 inch: 364 patients	Not assessed	Not assessed
Vu et al., 2008	Retrospective clinical trial	G. 0.022-inch: 91 patients	Not assessed	Not assessed
Detterline et al., 2010	Retrospective clinical trial	G. 0.018-inch: 613 patients	G. 0.018 inch: 16.5	0.4-month difference in favor of 0.018-inch slot (P < .05)
Detterline et al., 2010	Retrospective clinical trial	G. 0.022 inch: 215 patients	G. 0.022 inch: 17.7	0.4-month difference in favor of 0.018-inch slot (P < .05)

G. = Group