Table 5:

Oxygenation, ventilation and radiographic conditions sufficient for initiating a weaning trial

	Intubated Patients	Non-Intubated Patients
Oxygenation*	■ FiO2 consistently ≤ 60% ■ PEEP ≤ 10 cmH2O ■ PaO2 ≥ 70 mmHg	■ PaO2 ≥ 70 mmHg on no more than a moderate amount of supplemental O2 (example: ≤6 LPM NC or facemask, or ≤40LPM with FiO2 ≤0.3 on high flow nasal cannula)
Ventilation	■ Tidal volume ≤ 6mL/kg PBW ■ Plateau pressure ≤ 28 cmH2O ■ Respiratory rate ≤ 28 bpm ■ ABG demonstrates acceptable pH and PaCO2 based on the patient’s clinical condition without excessive work of breathing	■ ABG demonstrates acceptable pH based on the patient’s clinical condition without excessive work of breathing
Imaging	Chest radiograph demonstrates improvement in appearance