Table 2.
Differentially Expressed Genes Between the Control, MPTP, and MPTP-DZF Groups Obtained from the Analysis of the Mice Midbrain Transcriptomics Results
| Gene | Log2 (FC) | P-value |
|---|---|---|
| (A) Differentially Expressed Genes Between the MPTP Group and the Control Group | ||
| Nkx2-1 | 1.43 | 1.94E-19 |
| NR4A3 | 1.39 | 6.82E-24 |
| AC154734.1 | 1.31 | 1.52E-17 |
| Agrp | 1.24 | 9.57E-15 |
| Tma16 | 1.14 | 1.27E-22 |
| Hmgb2 | 1.13 | 1.37E-14 |
| Sytl4 | 1.11 | 6.86E-12 |
| Gm12840 | 1.08 | 3.23E-11 |
| Fmo2 | 1.03 | 4.57E-11 |
| Gpr50 | 1.00 | 4.64E-10 |
| Cyr61 | 0.99 | 8.71E-11 |
| Gm45221 | 0.96 | 3.86E-09 |
| Phactr3 | 0.94 | 1.46E-17 |
| Pomc | 0.94 | 2.33E-09 |
| Socs3 | 0.90 | 1.67E-08 |
| Gm20400 | 0.90 | 2.46E-08 |
| Isl1 | 0.90 | 2.96E-08 |
| Slmapos2 | 0.88 | 3.61E-08 |
| Tac2 | 0.86 | 3.24E-08 |
| Bsx | 0.86 | 1.31E-09 |
| Maff | 0.85 | 5.58E-08 |
| Rasd1 | 0.83 | 9.23E-08 |
| Elmsan1 | 0.83 | 1.27E-14 |
| Per1 | 0.82 | 1.21E-15 |
| Fosl2 | 0.82 | 2.55E-08 |
| Slco4a1 | 0.81 | 1.92E-07 |
| Irf7 | 0.80 | 4.65E-07 |
| 5830444B04Rik | 0.80 | 5.62E-07 |
| Btg3 | 0.79 | 8.37E-08 |
| Klf4 | 0.79 | 1.61E-10 |
| Fosb | 0.78 | 1.11E-06 |
| Vill | 0.77 | 2.08E-06 |
| Ciart | 0.74 | 7.62E-08 |
| Usp53 | 0.73 | 8.88E-13 |
| Adamts1 | 0.72 | 7.87E-08 |
| Fyb | 0.72 | 1.02E-05 |
| Gal | 0.71 | 1.19E-05 |
| Gm43300 | 0.71 | 1.28E-05 |
| Kctd15 | −0.71 | 2.61E-07 |
| Fam60a | −0.72 | 9.48E-06 |
| P2ry13 | −0.72 | 5.47E-06 |
| Arc | −0.72 | 4.75E-07 |
| A330023F24Rik | −0.73 | 2.44E-09 |
| Gm15535 | −0.73 | 5.09E-06 |
| Oraov1 | −0.74 | 1.75E-08 |
| Trim59 | −0.74 | 2.10E-08 |
| Cldn5 | −0.78 | 6.54E-10 |
| Sall1 | −0.84 | 7.83E-13 |
| Zfp366 | −0.85 | 1.47E-07 |
| (B) Differentially Expressed Genes Between MPTP-DZF Group and MPTP Group | ||
| Col6a1 | −0.71233 | 5.78E-09 |
| Slc47a1 | −0.73005 | 4.36E-08 |
| Gal | −0.73546 | 4.29E-08 |
| Fam179a | −0.7487 | 3.32E-08 |
| Adamtsl3 | −0.76488 | 1.62E-08 |
| Crabp1 | −0.87835 | 1.79E-11 |
| Sytl4 | −0.89234 | 1.43E-11 |
| Pomc | −0.91733 | 8.34E-12 |
| Anpep | −0.92788 | 6.29E-12 |
| Hdc | −0.98231 | 3.65E-13 |
| Lbp | −1.0015 | 6.07E-15 |
| Col23a1 | −1.07021 | 7.71E-20 |
| Nkx2-1 | −1.11077 | 1.09E-18 |
| AC154734.1 | −1.18157 | 2.37E-21 |
| Isl1 | −1.2237 | 1.10E-19 |
| Agrp | −1.24157 | 2.11E-20 |
| Npy | −1.3124 | 1.39E-24 |