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. Author manuscript; available in PMC: 2021 Jul 27.
Published in final edited form as: Compr Physiol. 2013 Apr;3(2):693–739. doi: 10.1002/cphy.c110048

Figure 6.

Figure 6

Temperature corrected arterial blood gases obtained at near maximal and maximal exercise (cycle ergometer or treadmill running) in normal subjects [(A) n = 198; (B) and (C) n = 175)]. Data are, with permission, from references (15, 45, 76, 93, 94, 118, 121, 124, 219, 231, 251, 328, 357). The horizontal line in A and B defines the normal value and in C the limits of the expected increase in A-aDO2 with exercise as defined by Dempsey and Wagner (47). The arterial PO2 is lower and the PaCO2 and A-aDO2 higher with increasing aerobic capacity. Above a V˙O2max of 65 to 70 mL/kg/min the majority of individuals have significant gas exchange impairment although it is uncommon in individuals with a V˙O2max<50mL/kg/min.