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| Dual-topology channels | Oriented channels | |||||||
|---|---|---|---|---|---|---|---|---|
| WT/OCN- | WT/SCN- | WT/NO3- | WT/Cl- | WT/OCN- | WT/Cl- | E88Q/OCN- | E88Q/Cl- | |
| Ki,1 | 6.8 mM | 9.0 mM | 45 mM | 137 mM | 7.9 mM | 480 mM | 48.9 mM | 213 mM |
| Bmax1 | 0.5 | 0.5 | 0.5 | 0.5 | 1.0 | 1.0 | 1.0 | 1.0 |
| Ki,2 | 100 mM | 190 mM | 530 mM | 1.1 M | -- | -- | -- | -- |
| Bmax2 | 0.5 | 0.5 | 0.5 | 0.5 | -- | -- | -- | -- |
| Dual-topology channels | ||||||||
|---|---|---|---|---|---|---|---|---|
| E88Q/SCN- | E88Q/Cl- | |||||||
| Ki,1 | 398 mM | 542 mM | ||||||
| Bmax1 | 0.5 | 0.5 | ||||||
| Ki,2 | 1.2 M | 5.8 M | ||||||
| Bmax2 | 0.5 | 0.5 | ||||||
