Table 4.

IMA changes in the serum of pregnant women with different complications.

Pathology	No. enrolled, method	IMA value		Reference
		Normal pregnant women	Study group
Hyperemesis gravidarum	n = 45, ELISA	6.9 ± 0.3 ng/mL	8.2 ± 0.2 ng/mL	[141]
First trimester abortions	n = 60 n = 45, ELISA	Median 173.2 ng/mL Range 94.6–451.2 Median 43.4 ng/mL Range 1.1–320.3	Median 206.5 ng/mL Range 28.7–775.3 Median 63.7 ng/mL Range 20.1–285.2	[142] [57]
Recurrent first trimester abortions	n = 43, ACB	0.88 ± 0.10 ABSU	1.11 ± 0.08 ABSU	[143]
Ectopic pregnancy	n = 38, ACB	0.484 ± 0.089 ABSU	0.577 ± 0.117 ABSU	[144]
Hypertensive pregnancy disorders	n = 40, ACB	0.374 ± 0.114 ABSU	0.465 ± 0.154 ABSU	[145]
Preterm preeclampsia	n = 19, ACB	Median 115.01 kU/L Range 102.29–124.81	Median 126.5 kU/L Range 114.33–134.36	[146]
Preeclampsia	n = 57, ACB n = 47, n = 45	0.77 ± 0.24 ABSU 0.76 ± 0.07 ABSU 71.61 ± 09.58 U/mL	1.24 ± 0.30 ABSU 0.80 ± 0.07 ABSU 106.92 ± 15.20 U/mL	[147] [148] [149]