REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
J1 (BRG1/BRM)	Khavari et al., 1993	N/A
H3K27Ac	Abcam	Cat# ab4729, RRID: AB_2118291
RNA pol II	Abcam	Cat# ab817, RRID:AB_306327
GATAD2B	Novus	Cat# NB100–60646, RRID:AB_922172
HDAC2	Thermo Fisher Scientific	Cat# PA1–861, RRID:AB_2118520
STAG2	Gift from Dr. Hongtao Yu, UTSW	N/A
BRG1(G7)	Santa Cruz Biotechnology	Cat# sc-17796, RRID:AB_626762
SMC3	Santa Cruz Biotechnology	Cat# sc-376352, RRID:AB_10989741
BAF53b	Wu et al., 2007	N/A
BAF170	Wang et al., 1996	N/A
GAPDH	Sigma-Aldrich	Cat# G9545, RRID:AB_796208
H3S10P	Cell Signaling Technology	Cat# 9701, RRID:AB_331535
Rabbit BRG1-S1382 phospho-specific antibody	Generated against peptide antigen VDYSD(pS)LTEKQ by Ab-Mart (Shanghai)	N/A
c-FOS	Cell Signaling Technology	Cat# 2250, RRID:AB_2247211
Chemicals, peptides, and recombinant proteins
PolyJet	Signagen	Cat# SL100688
Poly-L-ornithine	Sigma Aldrich	Cat# P4957
Fibronectin	Sigma Aldrich	Cat# F1141
Neurobasal medium	GIBCO	Cat# 21103049
B27 plus supplement	GIBCO	Cat# A3582801
TTX	Tocris	Cat# 1078
APV	Tocris	Cat# 0106
PFI-3	Tocris	Cat# 5072
C646	Tocris	Cat# 4200
Nimodipine	Tocris	Cat# 0600
KN93	Tocris	Cat# 1278
U0126	Tocris	Cat# 1144
TRIzol reagent	ThermoFisher Scientific	Cat# 15596018
iScript cDNA synthesis kit	Bio-Rad	Cat# 1708891
PFA	ELECTRON MICROSCOPY SCIENCES	Cat# 15710
DSG	Pierce	Cat# A35392
Protein A-coated magnetic Dynabeads	Invitrogen	Cat# 10002D
2X Sample Buffer	Bio-Rad	Cat# 1610737
FastFlow Sepharose Protein A beads	GE Healthcare	Cat# GE17–5280-01
SacI	New England Biolabs	Cat# R0156S
BgIII	New England Biolabs	Cat# R0144S
NcoI	New England Biolabs	Cat# R0193S
T4 DNA ligase	New England Biolabs	Cat# M0202S
Critical commercial assays
Illumina RNA-Seq Preparation Kit	Illumina	Cat# RS-122–2001
High-sensitivity colorimetric ATPase assay kit	Innova Biosciences	Cat# 601–0120
Silver staining kit	Invitrogen	Cat# LC6070
Nextra kit	Illumina	Cat# FC-121–1030
Deposited data
Genomic Data (combined)	NCBI	GEO: GSE174585
ATAC-seq	NCBI	GEO: GSE174579
BRG1 CHIP-seq	NCBI	GEO: GSE174581
RNA-seq (wt, Brg1cko)	NCBI	GEO: GSE174583
RNA-seq (WT, SA, SE)	NCBI	GEO: GSE174584
Experimental models: Cell lines
Human: HEK293T cells	ATCC	Cat# CRL-1573
Human: SW13 cells	ATCC	Cat# CCL-105
Mouse: Primary Cortical Neuron	Wu et al., 2007; Zhang et al., 2015	N/A
Experimental models: Organisms/Strains
Mouse: Brg1F/F BAF53b-Cre (Brg1cko),	Zhang et al., 2015	N/A
Mouse: Brg1-SA (SA), Brg1-SE (SE)	This paper	N/A
Oligonucleotides
	See Table S4	N/A
Recombinant DNA
pSin4-EF2-IRES-Puro-BRG1	Zhan et al., 2011	N/A
pSin4-EF2-IRES-Puro-BRM	Zhan et al., 2011	N/A
pSin4-EF2-IRES-Puro-BRG1-SA	This paper	N/A
pSin4-EF2-IRES-Puro-BRG1-SE	This paper	N/A
pSin4-EF2-IRES-Puro-BRG1-KR	Zhan et al., 2011	N/A
Software and algorithms
Kallisto program	Bray et al., 2016	https://pachterlab.github.io/kallisto/
EdgeR program	McCarthy et al., 2012	https://bioconductor.org/
Mascot search engine (version 2.3)	Perkins et al., 1999	https://www.matrixscience.com/
Bowtie 2	Langmead and Salzberg, 2012	http://bowtie-bio.sourceforge.net/bowtie2/index.shtml
MACS2	Zhang et al., 2008	https://github.com/macs3-project/MACS
BWA aligner	Li and Durbin, 2009	https://github.com/lh3/bwa
SICER	Zang et al., 2009	https://zanglab.github.io/SICER2/#introduction