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. 2021 May 18;65(6):e02658-20. doi: 10.1128/AAC.02658-20

FIG 1.

FIG 1

Possible mechanisms through which stress conditions could accelerate the evolution and spread of resistance genes. Drugs present at subinhibitory concentrations in body compartments may act as inducers, leading to increases (arrows) in mutagenesis (Mut) and horizontal gene transfer (HGT) by means of an ROS/SOS response.