TABLE 4.
Virions and caRNA area covered by any drug response and ARV-covered virus at concentrations greater than the IC50
| Drug | FDC-trapped virions |
Cell-associated RNA |
||||
|---|---|---|---|---|---|---|
|
n (n BLQ) |
Median (range) % of virus area covered by ARV | Median (range) % of ARV-covered virus >IC50 (BLQs excluded) |
n (n BLQ) |
Median (range) % of virus area covered by ARV |
Median (range) % of ARV-covered virus >IC50 (BLQs excluded) |
|
| FTC | 4 (3) | 0.34 (0–2.5) | 100 (100–100) | 6 (3) | 0 (0–3.1) | 0 (0–0) |
| TFV | 4 (2) | 8.3 (0–19) | 100 (100–100) | 6 (2) | 8.6 (0–29) | 100 (100–100) |
| EFV | 1 (0) | 10 | 100 (100–100) | 1 (0) | 13 (13–13) | 100 (100–100) |
| RAL | 1 (1) | 0.4 | 1 (1) | 0.7 (0.7–0.7) | ||
| MVC | 3 (0) | 69 (68–83) | 100 (100–100) | 5 (0) | 74 (51–81) | 100 (100–100) |
| ATV | 3 (2) | 2.6 (0–17) | 100 (100–100) | 5 (2) | 2.0 (0–32) | 100 (0–100) |
| Cumulative | 4 | 72 (11–100) | 6 | 79 (13–81) | ||