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. 2021 May 18;65(6):e00019-21. doi: 10.1128/AAC.00019-21

TABLE 4.

Virions and caRNA area covered by any drug response and ARV-covered virus at concentrations greater than the IC50

Drug FDC-trapped virions
Cell-associated RNA
n
(n BLQ)
Median (range) % of virus area covered by ARV Median (range) % of ARV-covered virus >IC50
(BLQs excluded)
n
(n BLQ)
Median (range) % of virus area
covered by ARV
Median (range) % of ARV-covered virus >IC50
(BLQs excluded)
FTC 4 (3) 0.34 (0–2.5) 100 (100–100) 6 (3) 0 (0–3.1) 0 (0–0)
TFV 4 (2) 8.3 (0–19) 100 (100–100) 6 (2) 8.6 (0–29) 100 (100–100)
EFV 1 (0) 10 100 (100–100) 1 (0) 13 (13–13) 100 (100–100)
RAL 1 (1) 0.4 1 (1) 0.7 (0.7–0.7)
MVC 3 (0) 69 (68–83) 100 (100–100) 5 (0) 74 (51–81) 100 (100–100)
ATV 3 (2) 2.6 (0–17) 100 (100–100) 5 (2) 2.0 (0–32) 100 (0–100)
Cumulative 4 72 (11–100) 6 79 (13–81)