FIG 2.

Percentage survival of mice in each treatment group following challenge with aerosolized F. tularensis. Mice were challenged with a mean retained dose of 272 CFU of F. tularensis by the inhalational route and treated with finafloxacin (23.1 mg/kg) every 8 h by the oral route or ciprofloxacin (30 mg/kg) every 12 h by the i.p. route. Control animals received substances by the oral (vehicle) or i.p. (PBS) route. Regimens were initiated at 24 (A) or 72 (B) hours postchallenge for 3 or 7 days. **, P < 0.01; ****, P < 0.0001.