Table 1.

Module search results for the analyzed datasets. LCC = largest connected component.

Disease name	Number of LCC nodes		Number of LCC edges		Number of total interactions
	observation	p-value	observation	p-value	observation	p-value
Ankylosing spondylitis	216	0.6	825	0.005	827	0.008
Crohn’s disease	399	2E-13	1120	3E-39	1147	2E-43
Chronic obstructive pulmonary disease (COPD)	163	0.0002	409	0.0002	418	0.0003
Chronic spontaneous urticaria	183	0.5	444	0.1	476	0.02
Community-acquired pneumonia	421	0.01	1347	1E-11	1359	2E-11
Common variable immunodeficiency	25	0.02	24	0.03	30	0.01
COVID-19	314	0.00001	441	3E-9	514	5E-17
Dermatomyositis	11	2E-11	23	2E-25	24	5E-17
H3N2 flu	170	0.03	270	0.001	282	6E-4
H1N1 flu	278	0.01	1309	2E-25	1331	5E-27
Inflammatory bowel disease	412	5E-16	1139	9E-38	1161	7E-42
Inclusion body myositis	3	0.01	4	0.01	5	0.007
Infective endocarditis	202	0.05	359	0.003	373	0.001
Primary lung cancer	333	0.0006	1185	2E-24	1192	2E-24
Polymyositis	12	0.004	14	0.00004	16	0.0002
Rheumatoid arthritis	178	0.03	321	1E-5	343	2E-7
Sarcoidosis	476	0.04	1731	4E-22	1745	3E-22
SARS	33	0.04	62	2E-6	65	3E-6
Septic shock	363	0.001	1202	1E-13	1223	6E-15
Tuberculosis	469	0.006	1829	8E-22	1843	7E-22
Ulcerative colitis	329	0.05	488	0.04	508	0.05
Venous thromboembolism	513	0.04	2975	0.00002	2977	0.00003