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. 2021 Jul 28;142:111954. doi: 10.1016/j.biopha.2021.111954

Table 3.

Drugs used for the diseases identified by the network module separation approach and RWR. * indicates drugs identified by SAveRUNNER. Drugs currently under investigation in clinical trials, as reported in DrugBank, are highlighted in bold .

Network module separation
Random Walk with Restart
Septic shock Crohn’s disease H1N1 flu Dermatomyositis Polymyositis
Epinephrine* Mesalazine* Acetaminophen* Corticotropin
Norepinephrine* Sulfasalazine* Cetirizine* Methylprednisolone
Naloxone Adalimumab Chlorpheniramine* Betamethasone
Budesonide Phenylephrine* Bupivacaine
Infliximab Pseudoephedrine* Methylprednisolone hemisuccinate
Naproxen
Oseltamivir
Salbutamol
Acetylsalicylic acid
Ascorbic acid
Methotrexate Methotrexate
Triamcinolone Triamcinolone
Prednisolone Prednisolone
Prednisone Prednisone
Hydrocortisone Hydrocortisone