Table 1.
In vitro antistaphylococcal activity of CF-296
| Straina | Typeb | MIC (μg/ml) | MBEC (μg/ml) |
|---|---|---|---|
| IDRL-6169 | MRSA | 0.5 | 1 |
| MW2 | MRSA | 1 | 1 |
| ATCC BAA-42 | MRSA | 1 | 1 |
| JMI 227 | MRSA | 0.5 | 1 |
| JMI 21489 | MRSA | 1 | 1 |
| ATCC 29213 | MSSA | 1 | 0.5 |
| JMI 7141 | MSSA | 1 | 1 |
| JMI 3830 | MSSA | 1 | 1 |
| JMI 7140 | MSSA | 1 | 1 |
| JMI 7441 | MSSA | 1 | 1 |
a
Strain MW2 (NRS 123) was obtained from BEI Resources (NIAID, NIH); ATCC strains were obtained from the American Type Culture Collection (Manassas, VA); JMI strains were obtained from JMI Laboratories (North Liberty, IA) and are described in Watson et al. (13).
b
MSSA, methicillin-susceptible S. aureus.