TABLE 3.
Broth microdilution of released CSP over a 7-day incubation period
| Species | Strain | CSP-loaded CS eluent concn (μg/ml)a |
||||||
|---|---|---|---|---|---|---|---|---|
| Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | ||
| Candida albicans | SC5314 | <0.15 | <0.15 | <0.15 | <0.15 | <0.15 | <0.15 | <0.15 |
| ATCC 10231 | <0.15 | <0.15 | 0.3 | 0.3 | 0.3 | 0.3 | 0.6 | |
| Candida glabrata | ATCC 2001 | 0.6 | 0.3 | 0.6 | 0.6 | 1.2 | 1.2 | 1.2 |
| Candida auris | NCPF 8978 | 1.2 | 1.2 | 1.2 | 1.2 | 1.2 | 1.2 | 1.2 |
| NCPF 8973 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 | |
| Malessezia furfur | NCPF 3349 | 1.2 | 0.6 | 0.6 | 0.6 | 1.2 | 1.2 | 1.2 |
| Candida tropicalis | BC064 | <0.15 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 |
| Candida parapsilosis | NCPF 8334 | 1.2 | 1.2 | 2.3 | 2.3 | 4.5 | 4.5 | 4.5 |
| Candida haemolunii | DSM 70624 | <0.15 | <0.15 | <0.15 | <0.6 | <0.3 | <0.3 | <0.6 |
| Trichosporon spp. | >76 | >76 | >76 | >76 | >76 | >76 | >76 | |
| Rhodotorula spp. | 38 | 38 | >76 | >76 | >76 | >76 | >76 | |
| Aspergillus fumigatus | NCPF 7367 | 1.2 | 1.2 | 1.2 | 1.2 | 0.6 | 19 | 19 |
| Aspergillus brasiliensis | ATCC 16404 | 0.3 | 0.3 | 0.3 | 0.3 | <0.15 | 0.6 | 0.6 |
| Rhizopus spp. | ||||||||
| Scedosporium spp. | 19 | 38 | 38 | 38 | 19 | 38 | 19 | |
The table is representative of concentration dilutions extracted from 5 ml of approximately 76 μg/ml eluent of CSP-inoculated Stimulan Rapid Cure beads, diluted 1:1 across a plate with concentrations ranging from 76 to 0.15 μg/ml. Note that there was no inhibition for Rhizopus spp.