TABLE 1.
Cohort demographicsa
| Characteristic | Value |
|||||
|---|---|---|---|---|---|---|
| PROVIDE cohort |
CBC cohort |
|||||
| Cases (N = 93) | Controls (N = 336) | P value | Cases (N = 50) | Controls (N = 110) | P value | |
| Male sex (N [%]) | 52 (56) | 179 (53) | 0.74 | 26 (52) | 44 (40) | 0.21 |
| WAZ (Z-score) | ||||||
| Enrollment | −1.29 | −1.3 | 0.93 | −1.53 | −1.1 | 0.01 |
| 1 yr | −1.27 | −1.14 | 0.32 | −1.35 | -0.92 | 0.02 |
| HAZ (Z-score) | ||||||
| Enrollment | −0.91 | −0.89 | 0.83 | −0.95 | −0.84 | 0.53 |
| 1 yr | −1.6 | −1.49 | 0.49 | −1.64 | −1.24 | 0.09 |
| No. of diarrheal events (mean [SE]) | 4.4 (0.33) | 3.6 (0.13) | 0.02 | 5.4 (0.34) | 3.3 (0.26) | 4.3 × 10−6 |
| Age at first diarrheal event (days) (mean [SE]) | 142 (9.23) | 124 (4.53) | 0.09 | 128 (11.88) | 130 (8.58) | 0.87 |
| Age at first Shigella-associated diarrheal event (days) (mean [SE]) | 257 (8.59) | 282 (10.79) | ||||
| Days of exclusive breastfeeding (mean [SE]) | 114 (5.97) | 119 (3.32) | 0.5 | 113 (9.31) | 119 (6.57) | 0.58 |
| Avg Ruuska severity score for diarrheal events (mean [SE]) | 6.9 (0.21) | 7.4 (0.12) | 0.02 | 10.5 (0.29) | 10.2 (0.27) | 0.41 |
| Shared toilet (N [%]) | 76 (82) | 292 (87) | 0.27 | 34 (68) | 80 (73) | 0.67 |
| No. of individuals in the household (mean [SE]) | 5.5 (0.3) | 5.2 (0.1) | 0.42 | 5.6 (0.3) | 5.3 (0.2) | 0.56 |
| Avg monthly income (Taka) (mean [SE]) | 13,000 (1037) | 13,000 (518.3) | 0.88 | 18,000 (1838.5) | 16,000 (1239.5) | 0.49 |
a
The distribution of clinical phenotypes and baseline demographics and clinical measures for the PROVIDE and CBC studies. Continuous variables are presented with their mean (standard error [SE]). Categorical values are presented with their observed frequency and column-wise percentage. 1 Bangladeshi taka = $0.012.