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2093 docked into a comparative model of CpMetRS. 2093 is coded with C (cyan), N (blue), and O (red). The resistance mutations D243 and T246 are labeled. D243 forms a salt bridge with H63. This salt bridge is at 3.8 Å from both C-6 and C-7 of the imidazo[4,5-b]pyridine bicyclic system. T246 is within van der Waals distance of the F242 phenyl ring. 2093 is also shown as a stick diagram for reference.
