TABLE 1.
Sensitivity for CIN2+ and CIN3+ and specificity for ≤CIN1 of Alinity m, HC2, RealTime, and cobas in the total study population and in women ≥30 years old
| Test and group | Sensitivity for CIN2+ |
Sensitivity for CIN3+ |
Specificity for ≤CIN1 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| % | 95% CI | n/N | % | 95% CI | n/N | % | 95% CI | n/N | |
| Total study population | |||||||||
| Alinity m | 98.4 | 94.4–99.8 | 124/126 | 100.0 | 95.5–100.0 | 81/81 | 91.1 | 89.3–92.6 | 1,104/1,212 |
| HC2 | 96.0 | 91.0–98.7 | 121/126 | 97.5 | 91.4–99.7 | 79/81 | 90.1 | 88.3–91.7 | 1,092/1,212 |
| RealTime | 96.8 | 92.1–99.1 | 122/126 | 98.8 | 93.3–99.9 | 80/81 | 91.7 | 90.1–93.2 | 1,112/1,212 |
| cobas | 96.0 | 91.0–98.7 | 121/126 | 97.5 | 91.5–99.7 | 79/81 | 91.4 | 89.7–93.0 | 1,100/1,203 |
| Women ≥30 yr old | |||||||||
| Alinity m | 99.0 | 94.4–100.0 | 97/98 | 100.0 | 94.6–100.0 | 66/66 | 93.8 | 92.1–95.2 | 946/1,009 |
| HC2 | 95.9 | 89.8–98.9 | 94/98 | 97.0 | 89.5–99.6 | 64/66 | 92.9 | 91.1–94.4 | 937/1,009 |
| RealTime | 96.9 | 94.4–100.0 | 95/98 | 98.5 | 94.6–100.0 | 65/66 | 94.5 | 92.7–95.7 | 954/1,009 |
| cobas | 96.9 | 91.3–99.4 | 95/98 | 97.0 | 89.5–99.6 | 64/66 | 94.1 | 92.5–95.5 | 943/1,002 |