TABLE 3.
Overall hrHPV and type-specific concordance between Alinity m and RealTime assessed on all samples with valid HPV results included in the VALGENT-3 panel (n = 1,593)
| HPV typeb | Value (no.) by test result |
Concordance (%) | Kappaa | |||||
|---|---|---|---|---|---|---|---|---|
| Alinity m+ | RealTime+ | Alinity m+/RealTime+ | Alinity m+/RealTime− | Alinity m−/RealTime+ | Alinity m−/RealTime− | |||
| 14 hr types | 349 | 324 | 324 | 25 | 8 | 1,236 | 97.93 | 0.9384 |
| HPV-16 | 116 | 113 | 113 | 3 | 0 | 1,477 | 99.81 | 0.9859 |
| HPV-18 | 34 | 31 | 30 | 4 | 1 | 1,558 | 99.69 | 0.9215 |
| HPV-16/18 | 145 | 139 | 138 | 7 | 1 | 1,454 | 99.56 | 0.9729 |
a
Kappa legend (adapted from Landis and Koch [36]) for levels of agreement: 1.00 ≥ κ > 0.80, excellent; 0.80 ≥ κ > 0.60, good; 0.60 ≥ κ > 0.40, moderate; 0.40 ≥ κ > 0.20, fair; 0.20 ≥ κ > 0.00, poor.
b
HPV-16, -18, and -16/18 indicate that particular HPV types are present as a single or multiple infections.