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. 2021 May 18;65(6):e00002-21. doi: 10.1128/AAC.00002-21

FIG 1.

FIG 1

Relationships between the daily dose of colistin base activity (CBA), expressed as milligrams per day (A) and as milligrams per kilogram per day (B), needed for each 1 mg/liter of the average steady-state plasma concentration of colistin (Css,avg) and creatinine clearance (in milliliters per minute). In panel A, data for patients with SIRS (filled symbols; R2 = 0.81) and without SIRS (empty symbols; R2 = 0.74) were regressed separately.