TABLE 2.

Type of infection, Gram-negative organism implicated, coadministered antimicrobial agents, outcome, and renal toxicity^a

Patient	Type of infection	Treatment duration (days)	Organism implicated	Site of isolation	Coadministered antimicrobial agents	Outcome	Renal toxicity
1	VAP	28	P. aeruginosa	BA	TZP, CLR	Death	No
2	Fever unresponsive to broad-spectrum ABx, colonization with CR, P. aeruginosa	10	P. aeruginosa	Throat swab	MEM, AMK, TEC	Cure	No
3	Possible VAP, colonization with P. aeruginosa and A. baumannii	20	P. aeruginosa, A. baumannii	BA	CIP, TGC	Cure	No
4	VAP	20	P. aeruginosa	BAL fluid	FEP, TEC	Cure	No
5	Sepsis	19	A. baumannii	Blood	MEM, AMK, LZD	Cure	No
6	Bacteremia	10	K. pneumoniae	Blood	MEM, GEN, SXT	Cure	No
7	VAP	20	A. baumannii	BA	MEM, AMK	Clinical improvement	No
8	VAP	10	A. baumannii	BA	MEM, TEC	Cure	No
9	Bacteremia	10	A. baumannii	Blood	MEM, GEN, TZP	Cure	No
10	Septic shock, VAP	15	Stenotrophomonas maltophilia	BAL fluid	MEM	Death	No
11	Septic shock	17	P. aeruginosa	Blood	MEM, VAN, RIF, CIP, AZM	Clinical improvement	No
12	VAP, bacteremia	10	A. baumannii	Blood, BA	TGC, TEC, AMK, TZP	Cure	No
13	Sepsis	23	K. pneumoniae	Blood	MEM, GEN, TEC, TGC, FOF, SXT	Death	Yes
14	Surgical trauma infection	20	A. baumannii	Trauma site, BAL fluid	MEM, LZD, TGC	Cure	No
15	VAP	28	A. baumannii, K. pneumoniae, P. aeruginosa	BAL fluid	GEN, TGC	Cure	No
16	Septic shock	20	P. aeruginosa	Blood	MEM, GEN, TZP, SXT	Clinical improvement	No
17	Sepsis	17	S. maltophilia	Blood	CIP, TEC	Cure	No

^aABx, antibiotics; AMK, amikacin; BA, bronchial aspirate; BAL, bronchoalveolar lavage; CIP, ciprofloxacin; CLR, clarithromycin; CR, carbapenem-resistant; FEP, cefepime; FOF, fosfomycin; GEN, gentamicin; LZD, linezolid; MEM, meropenem; RIF, rifampin; SXT, trimethoprim-sulfamethoxazole; TEC, teicoplanin; TGC, tigecycline; TZP, piperacillin-tazobactam; VAN, vancomycin; VAP, ventilator-associated pneumonia.