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. 2021 May 21;41(6):e00380-20. doi: 10.1128/MCB.00380-20

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FIG 1 — LINC01006 promotes cell proliferation, migration, and EMT in LUAD. (A) The expression of LINC01006 in healthy lung tissues and LUAD tumor tissues was analyzed by examining the GEPIA database (http://gepia2.cancer-pku.cn/#index). (B) LINC01006 expression in human healthy lung epithelial cell line (BEAS-2B) and LUAD cell lines (PC9, H1650, H1975, and A549) was evaluated by RT-qPCR. (C) RT-qPCR was applied to assess the knockdown efficiency of sh-LINC01006#1, sh-LINC01006#2, and sh-LINC01006#3. (D) Colony formation assay was implemented to investigate the proliferative capacity of LUAD cells. (E) Cell migration before and after LINC01006 knockdown was examined by transwell assay. (F) The protein levels of epithelial marker (E-cadherin) and mesenchymal markers (N-cadherin and vimentin) were analyzed by Western blotting. *, P < 0.05; **, P < 0.01.