Table 1.
Recent studies of combined stem cell and gene therapy for ischemic heart disease
| Cells type | Genes | Transfection Methods | Ref |
| Mouse Cardiac Progenitor Cells | Akt (+) | Renti-virus infection | [98] |
| Human Bone Marrow-derived Stem Cells | Akt (+) | Retro-virus infection | [99] |
| Human Mesenchymal Stem Cells | SDF-1 (+) | Retro-virus infection | [102] |
| Rat Mesenchymal Stem Cells | CXCR4 (+) | Retro-virus infection | [103] |
| Cells type | Genes | GE Techniques | Ref |
| Human Umbilical Cord Blood-derived Mesenchymal Stem Cells | VEGF (+) | TALEN | [126] |
| Human Umbilical Cord Blood-derived Mesenchymal Stem Cells | HGF (+) | TALEN | [127] |
| Human Embryonic Stem Cells | MESP1(+) | TALEN | [129] |
| Human Umbilical Cord Blood-derived Mesenchymal Stem Cells | LEF1 (+) | CRISPR/Cas9 | [132] |
| rhesus macaque induced pluripotent stem cells | NIS (+) | CRISPR/Cas9 | [133] |
| Human Umbilical Cord Blood-derived Mesenchymal Stem Cells | B2M (−) | CRISPR/Cas9 | [136] |
| Amniotic Mesenchymal Stem Cells | IL-10 (+) | TALEN | [137] |
| Bone Marrow-derived Mesenchymal Stem Cells | IL-10 (+) | CRISPR/Cas9 | [138] |