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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Stroke. 2021 Jun 17;52(8):2609–2617. doi: 10.1161/STROKEAHA.120.033797

Table 4.

Co-sibling analyses for gestational age at birth (1973–1994) in relation to stroke risk (1991–2015), Sweden.

Cases HR (95% CI)*
Any stroke
Preterm (<37 wks) 215 1.16 (0.92, 1.47)
Early term (37–38 wks) 598 1.07 (0.92, 1.24)
Full-term (39–41 wks) 2,509 Reference
Per additional week (trend) 0.98 (0.95, 1.01)
Hemorrhagic stroke
Preterm (<37 wks) 117 1.05 (0.77, 1.45)
Early term (37–38 wks) 365 1.06 (0.88, 1.29)
Full-term (39–41 wks) 1,526 Reference
Per additional week (trend) 1.00 (0.96, 1.04)
Ischemic stroke
Preterm (<37 wks) 79 1.17 (0.79, 1.73)
Early term (37–38 wks) 207 1.09 (0.83, 1.43)
Full-term (39–41 wks) 869 Reference
Per additional week (trend) 0.96 (0.91, 1.01)
*

Adjusted for shared familial (genetic and/or environmental) factors in addition to specific child characteristics (age, sex, birth year, birth order), maternal characteristics (age, education, birth country or region, BMI, smoking, preeclampsia, other hypertensive disorders, diabetes), and paternal characteristics (age, education).