Table 1B.
Characteristic | No. of Patients (%) | p – value | |
---|---|---|---|
KEAP1 / NFE2L2 wt (n = 48) |
KEAP1 / NFE2L mt (n = 18) |
||
Median age, range | 66 (45 – 81) | 69 (65 – 85) | 0.14 |
Sex | 0.72 | ||
Female | 21 (44) | 7 (39) | |
Male | 27 (56) | 11 (61) | |
Performance Status | 0.36 | ||
ECOG 0 | 30 (63) | 9 (50) | |
ECOG 1 | 18 (37) | 9 (50) | |
Gross Tumor Volume (cc) | |||
Median, Range | 109.7 (7 – 600.7) | 143.4 (13.5 – 392.6) | 0.98 |
Histology | 0.39 | ||
Adenocarcinoma | 34 (71) | 12 (67) | |
Squamous Cell | 11 (23) | 3 (16) | |
Other | 3 (6) | 3 (16) | |
PDL1 Expression | 0.76 | ||
< 1% | 15 (31) | 6 (33) | |
≥ 1% | 24 (50) | 10 (56) | |
Not available | 9 (19) | 2 (11) | |
PDL1 ≥50% | 0.41 | ||
< 50% | 26 (54) | 13 (72) | |
≥ 50% | 13 (27) | 3 (17) | |
Not available | 9 (19) | 2 (11) | |
AJCC 8th Overall Stage | 0.59 | ||
IIIA | 15 (31) | 5 (28) | |
IIIB | 25 (52) | 8(44) | |
IIIC | 8 (17) | 5 (28) | |
Smoking History | 0.45 | ||
Yes | 45 (94) | 18 (100) |