Engineering DCs with polymer nanoparticles to enhance cross-presentation. a Schematic diagram of ex vivo engineered DCs for efficient anti-tumor immunity. b CTL activity represented by the mean percentage of tumor cell lysis. c Proliferation of antigen-specific CD8 + T cells. Mean ± SD (*P < 0.05, **P < 0.01).
Reprinted from Adv Funct Mater, 26(44), Kim SY, Phuengkham H, Noh YW, Lee HG, Um SH, Lim YT, Immune Complexes Mimicking Synthetic Vaccine Nanoparticles for Enhanced Migration and Cross-Presentation of Dendritic Cells, 8072–82 [58]