TABLE 1.
Clinical characteristics of liver cirrhosis and HCC patients.
| Group | Set 1 (lectin; 16O/18O labeling) | Set 2 (label free) | Set 3 (MRM) | |||
|---|---|---|---|---|---|---|
| LC | HCC | LC | HCC | LC | HCC | |
| Number | 60 | 60 | 7 | 7 | 12 | 12 |
| Age | 47.40 ± 11.73 | 49.65 ± 11.55 | 48.57 ± 8.02 | 47.4 ± 10.27 | 50.13 ± 8.55 | 51.0 ± 10.29 |
| Gender (M/F) | 50/10 | 55/5 | 6/1 | 6/1 | 8/4 | 11/1 |
| ALT, U/L | 30 (5–216) | 42 (12–428) | 32 (17–121) | 36 (15–199) | 27 (17–121) | 53 (15–199) |
| AST, U/L | 35 (8–182) | 38 (15–355) | 33 (19–145) | 50 (24–220) | 34 (19–145) | 43 (24–220) |
| HBsAg+(%) a | 100 | 100 | 100 | 100 | 100 | 100 |
| AFP, ng/mL | 6.00 (1.2–65.1) | 153.3 (1.6–60500.0) | 3.86 (1.35–170.0) | 94.1 (1.41–60500.0) | 3.26 (1.35–170) | 73.76 (1.41–60500) |
ALT, alanine aminotransferase; AST, aspartate transaminase; HbsAg, hepatitis B surface antigen; AFP, alpha fetoprotein.
a
Normal results of HBsAg+ (%) are negative or nonreactive, meaning that no HBsAg was found; if the test is positive or reactive, it may mean active infection with HBV or chronic hepatitis B infection.