Table 2.

Multivariate cox regression analysis of non-HDL-C with cause-specific mortality.

	Event rate/ 1,000 person- years	Model I HR (95% CI), p-value	Model II HR (95% CI), p-value	Model III HR (95% CI), p-value
All-cause mortality
Non-HDL-C (as continuous variables, per 10 mg/dl increment)	20.75	0.97 (0.96, 0.98) <0.001	0.98 (0.97, 0.99) 0.004	0.98 (0.97, 0.99) 0.003
Non-HDL-C group, mg/dl
<130	24.19	1.33 (1.19, 1.49) <0.001	1.31 (1.17, 1.47) <0.001	1.29 (1.14, 1.46) <0.001
130–159	18.80	Reference	Reference	Reference
160–189	19.60	1.03 (0.90, 1.17) 0.672	1.04 (0.92, 1.19) 0.507	1.01 (0.88, 1.16) 0.899
190–219	19.55	1.03 (0.88, 1.20) 0.749	1.10 (0.94, 1.29) 0.249	1.01 (0.85, 1.19) 0.925
≥220	19.74	1.03 (0.84, 1.25) 0.784	1.24 (1.02, 1.51) 0.034	1.17 (0.95, 1.44) 0.135
P for trend		<0.001	0.036	0.01
Cardiovascular mortality
Non-HDL-C (as continuous variables, per 10 mg/dl increment)	4.50	1.01 (0.99, 1.03) 0.388	1.03 (1.00, 1.05) 0.027	1.02 (1.00, 1.05) 0.1
Non-HDL-C group, mg/dl
<130	4.65	1.16 (0.90, 1.50) 0.237	1.12 (0.87, 1.44) 0.391	1.07 (0.82, 1.41) 0.615
130–159	4.05	Reference	Reference	Reference
160–189	4.50	1.10 (0.84, 1.45) 0.479	1.13 (0.86, 1.48) 0.398	1.02 (0.76, 1.36) 0.913
190–219	4.57	1.12 (0.80, 1.57) 0.499	1.22 (0.87, 1.71) 0.239	1.05 (0.73, 1.51) 0.799
≥220	5.66	1.38 (0.95, 2.02) 0.095	1.75 (1.19, 2.55) 0.004	1.55 (1.03, 2.34) 0.037
P for trend		0.552	0.055	0.284

HR, hazard ratio; CI, confidence interval.

Model I adjust for none; model II adjust for age, gender, and race; model III adjust for age, gender, race, smoking, body mass index, systolic blood pressure, diabetes, and medicine use (antihypertensive drugs, hypoglycemic agents, and lipid-lowering drugs).