Table 4.

Subgroup analysis.

	N	All-cause mortality HR (95% CI) P-value		P for log likelihood ratio test	Cardiovascular mortality HR (95% CI) P-value		P for log likelihood ratio test
Cutoff value, mmol/l		<158	≥158		<190	≥190
Age
≥65	4,323	0.95 (0.93, 0.98) <0.001	1.00 (0.98, 1.03) 0.769	0.021	1.00 (0.96, 1.04) 0.896	1.02 (0.94, 1.11) 0.669	0.777
<65	7,846	0.93 (0.89, 0.97) <0.001	1.03 (1.01, 1.06) 0.018	<0.001	0.95 (0.89, 1.02) 0.164	1.11 (1.07, 1.15) <0.001	0.002
Gender
Male	5,783	0.91 (0.88, 0.93) <0.001	1.04 (1.01, 1.07) 0.014	<0.001	0.95 (0.91, 1.00) 0.046	1.12 (1.07, 1.17) <0.001	<0.001
Female	6,386	0.97 (0.94, 1.01) 0.117	1.01 (0.98, 1.04) 0.396	0.149	1.01 (0.96, 1.07) 0.63	1.03 (0.94, 1.13) 0.517	0.787
Race
Non-white	6,757	0.93 (0.90, 0.96) <0.001	1.04 (1.01, 1.07) 0.003	<0.001	0.97 (0.93, 1.02) 0.204	1.11 (1.06, 1.17) <0.001	0.002
White	5,412	0.95 (0.92, 0.98) <0.001	1.01 (0.98, 1.04) 0.462	0.015	1.00 (0.95, 1.05) 0.999	1.06 (0.98, 1.15) 0.157	0.327
Lipid-lowering drugs
No	9,768	0.93 (0.91, 0.96) <0.001	1.02 (1.00, 1.05) 0.034	<0.001	0.98 (0.95, 1.02) 0.397	1.09 (1.04, 1.14) <0.001	0.013
Yes	2,401	0.96 (0.91, 1.00) 0.061	1.03 (0.98, 1.09) 0.25	0.086	0.99 (0.91, 1.07) 0.779	1.11 (1.01, 1.22) 0.024	0.136
Body mass index, kg/m2
<25	2,422	0.92 (0.88, 0.95) <0.001	1.03 (0.98, 1.08) 0.227	0.002	0.98 (0.93, 1.05) 0.6	1.07 (0.93, 1.23) 0.323	0.346
≥25	9,491	0.95 (0.92, 0.98) <0.001	1.03 (1.00, 1.05) 0.023	<0.001	0.99 (0.95, 1.03) 0.699	1.10 (1.05, 1.15) <0.001	0.009

When analyzing a subgroup variable, age, gender, race, smoking, body mass index, systolic blood pressure, diabetes, and medicine use (antihypertensive drugs, hypoglycemic agents, and lipid-lowering drugs) were all adjusted except the variable itself.