Table 1.
Repeated measures analysis of variables possibly associated with the antibody response
| Model | Marginal means (MM) and p values |
|||
|---|---|---|---|---|
| Main effect |
Interaction Time∗Variable | |||
| T0 Group (MM) |
T1 Group (MM) |
T2 Group (MM) |
||
| Groups A B C D | Favours A (946.09) vs C (531.96) vs B (6.00) vs D (2.86) p 0.001 | Favours A (27 010.79) vs C (14 524.94) vs B (46 15.33) vs D (1186.27) p < 0.001 | Favours A (33 819.57) vs C (27 784.78) vs D (18 165.73) vs B (16 190.64) p < 0.001 | Interaction Time (T0 T1 T2) and Group signficant at p < 0.001 |
| Symptoms (Group A) | Symptoms (1015.78) vs No Symptoms (424.74) p 0.1650 | Favours Symptoms (27 923.57) vs No Symptoms (20 181.90) p 0.0271 | Symptoms (30 049.14) vs No Symptoms (34 323.54) p 0.2615 |
Interaction Time (T0 T1 T2) and Symptoms signficant at p < 0.001 |
| Age (all groups) | 18–30 y (65.70) vs 31–40 y (111.17) vs 41–50 y (170.26) vs 51–60 y (173.02) vs 60 y (165.35) or older p 0.2769 | 18–30 y (5051.60) vs 31–40 y (4766.96) vs 41–50 y (4580.01) vs 51–60 y (5473.81) vs 60 y (4551.94) or older p 0.7398 | 18–30 y (24 573.30) vs 31–40 y (21 270.20) vs 51–60 y (19 293.61) vs 41–50 y (18 851.72) vs 60 y or older (16 779.32) p < 0.0001 | Interaction Time (T0 T1 T2) and Age groups signficant at p < 0.001 |
| Sex (all groups) | Female (132.32) vs Male (147.75) p 0.6866 | Female (5009.80) vs Male (4793.47) p 0.6794 | Female (21 617) vs Male (18 254.82) p | Interaction Time (T0 T1 T2) and Sex signficant at p < 0.001 |
Group A, Seropostive exCOVID-19 health-care workers (HCW); group B, Seronegative exCOVID-19 HCW; group C, suspected previous infections; group D, naive individuals. Marginal means are means of IgG-RBD-S extracted from the model, representing average response for each considered variable (reported in the column “Model”).