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Frequency of adverse events reported following the first (D1) and the second (D2) dose of vaccine
| Adverse event | D1 n/N (%) | D2 n/N (%) | p (McNemar test) |
|---|---|---|---|
| Fatigue | 289/1935 (14.9) | 331/1935 (17.1) | <0.0001 |
| Fever | 51/1935 (2.6) | 433/1953 (22.4) | <0.0001 |
| Headache | 203/1935 (10.5) | 515/1935 (26.6) | <0.0001 |
| Malaise | 111/1935 (5.7) | 588/1935 (30.4) | <0.0001 |
| Myalgia | 140/1935 (7.2) | 640/1935 (33.1) | <0.0001 |
| Pain at injection site | 1475/1935 (75.3) | 1331/1935 (68.8) | <0.0001 |
