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. 2021 Jul 14;11:609882. doi: 10.3389/fonc.2021.609882

Table 3.

Multivariate survival analysis.

OS DSS
HR (95% CI) p-value HR (95% CI) p-value
Age
 <60 Reference Reference
 60-75 2.253 (1.646-3.086) <0.001* 1.815 (1.260-2.615) 0.001*
 ≥75 3.592 (2.639-4.890) <0.001* 2.645 (1.863-3.755) <0.001*
Gender
 Female Reference Reference
 Male 1.336 (1.061-1.681) 0.014* 1.340 (1.020-1.759) 0.036*
Primary Site
 UUT Reference Reference
 LUT 1.248 (0.940-1.657) 0.125 1.183 (0.837-1.671) 0.341
Surgery
 Yes Reference Reference
 No 1.301 (1.014-1.670) 0.039* 1.539 (1.136-2.084) 0.005*
Radiation
 Yes Reference Reference
 No 1.315 (0.829-2.087) 0.245 1.521 (0.810-2.858) 0.192
Chemotherapy
 Yes Reference Reference
 No 2.031 (1.595-2.585) <0.001* 2.405 (1.813-3.191) <0.001*
Ann Arbor Stage
 Stage I Reference Reference
 Stage II 1.013 (0.736-1.395) 0.938 1.069 (0.723-1.580) 0.738
 Stage III 1.113 (0.714-1.736) 0.636 1.325 (0.795-2.206) 0.280
 Stage IV 1.606 (1.202-2.146) 0.001* 1.835 (1.298-2.594) 0.001*

OS, Overall survival; DSS, disease specific survival; HR, Hazard ratio; CI, Confidence interval; UUT, Upper Urinary Tract; LUT, Lower Urinary Tract; *p < 0.05.