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. 2021 Mar 4;5(4):467–476. doi: 10.1002/ags3.12446

TABLE 2.

(a) List of studies comparing RPD and OPD (b) List of studies comparing RPD and LPD

(a) RPD vs OPD Comment Conversion P‐value Mortality P‐value Morbidity P‐value POPF P‐value Operative time P‐value Blood loss P‐value OS P‐value
Podda et al 7 Systematic review 90‐day Overall Overall
RPD (n = 1593) 4.7% 3.3% .840 64.4% .120 17.9% .810 461 min .000 352 ml .003 N.A NA
OPD (n = 12 046) 2.8% 68.1% 15.9% 384 min 588 ml N.A
Girgis et al 23 BMI ≥ 30.0 kg/m2 30‐day CD ≥ 3 Grade B C
RPD (n = 70) 0.0% 1.4% .368 35.7% 1.000 12.9% .039 381 min .003 250ml .001 N.A NA
OPD (n = 75) 5.3% 36.0% 28.0% 428 min 500ml N.A
Nassour et al 6 National data (NCDB) 90‐day
RPD (n = 626) 14.7% 3.8% .061 NA NA NA NA NA NA NA NA 22.0 M .755
OPD (n = 17,205) 5.6% NA NA NA NA 21.8 M
Shyr et al 24 Level 3 dissection 90‐day CD ≥ 3 Grade B C
RPD (n = 36) 2.9% 2.8% 1.000 13.9% NA 19.4% .082 576 min .137 263 ml <.001 85.70% .699
OPD (n = 19) 0.0% 0.0% 0.0% 600 min 600 ml 85.70%
(b) RPD vs LPD
Kamarajah et al 25 Systematic review 30‐day CD ≥ 3 overall
RPD (n = 1025) 12.0% <.001 2.0% .80 42.0% .90 19.0% .90 405 min .3 220 ml .1 NA NA
LPD (n = 2437) 26.0% 3.0% 41.0% 19.0% 418 min 287 ml NA
Liu et al 26 ) overall overall overall
RPD (n = 27) 0.0% .980 4.0% .98 29.6% .28 14.3% .89 387 min .015 219 ml .01 NA NA
LPD (n = 25) 4.0% 0.0% 44.0% 20.0% 442 min 334 ml NA
Nassour et al 27 National data (NCDB) 90‐day
RPD (n = 165) 17.0% 0 4.8% .93 NA NA NA NA NA NA NA NA 20.7 M .445
LPD (n = 1,458) 27.6% 5.6% NA NA NA NA 22.7 M

Abbreviations: OPD, open pancreatoduodenectomy; POPF, postoperative pancreatic fistula; RPD, robotic pancreatoduodenectomy; NCDB, National Cancer Database (in the USA).