Table 1. Baseline Characteristics of the Study Population*.
Parameter | Total (n = 76) | EP (n = 15) | NEP (n = 61) | P | |
---|---|---|---|---|---|
Mean age, years | 56.6 (22–77) | 57.2 | 56.4 | 0.83† | |
Radiation dose, Gy | 56.8 ± 8.2 | 56.1 ± 12.2 | 57.0 ± 7.0 | 0.70† | |
Sex | 0.51‡ | ||||
Male | 45 | 10 | 35 | ||
Female | 31 | 5 | 26 | ||
Genetic information | |||||
IDH mutation | 1.00§ | ||||
Mutant | 2 | 0 | 2 | ||
Wild-type | 74 | 15 | 59 | ||
MGMT promoter | 0.69‡ | ||||
Methylated | 37 | 8 | 29 | ||
Unmethylated | 39 | 7 | 32 | ||
Karnofsky performance score | 0.44§ | ||||
< 70 | 12 | 1 | 11 | ||
70 | 64 | 14 | 50 |
Data represent the number of patients, unless otherwise noted. *Data are mean ± standard deviation, †Calculated with student's t test, ‡Calculated with the chi-square test, §Calculated with Fisher's exact test. EP = early progression, IDH =isocitrate dehydrogenase, MGMT = O6-methylguanine-DNA methyltransferase, NEP = nonearly progression