Table 1. Clinical-Pathologic and Radiologic Characteristics of 90 Patients.
Characteristics | Total (n = 90) | |
---|---|---|
Mean age, years (range) | 57 (38–84) | |
Sex, male:female | 69:21 | |
No. of treated HCCs per patient | ||
1 | 76 (84.4) | |
2 | 13 (14.4) | |
3 | 1 (1.2) | |
Risk factors | ||
Hepatitis B | 67 (74.4) | |
Hepatitis C | 8 (8.9) | |
Alcoholic liver disease | 6 (6.7) | |
Hepatitis B and alcoholic liver disease | 4 (4.4) | |
Hepatitis C and alcoholic liver disease | 1 (1.1) | |
Cryptogenic liver cirrhosis | 4 (4.4) | |
Child-Pugh classification | ||
A | 82 (91.1) | |
B | 8 (8.9) | |
Median serum AFP (range), ng/mL | 16.9 (1.6–30741.3) | |
Pretreatment LI-RADS category* | ||
LI-RADS 4 | 15 (14.3) | |
LI-RADS 5 | 82 (78.0) | |
LI-RADS M | 1 (1.0) | |
LI-RADS TIV | 7 (6.7) | |
Type of locoregional treatment* | ||
Conventional TACE | 60 (57.0) | |
RFA | 25 (23.8) | |
TACE + RFA | 13 (12.4) | |
DEB - TACE | 3 (2.9) | |
TARE | 2 (1.9) | |
PEA | 1 (1.0) | |
DEB - TACE + RFA | 1 (1.0) | |
Type of surgery | ||
Surgical resection | 35 (38.9) | |
Living donor liver transplantation | 50 (55.6) | |
Deceased donor liver transplantation | 5 (5.6) | |
Histopathologic necrosis, %† | ||
0 | 1 (1.0) | |
1–50 | 26 (26.3) | |
51–99 | 40 (40.4) | |
100% (pathologically nonviable) | 32 (32.3) | |
Signal intensity on precontrast T1-WI* | ||
Iso- or hypointensity | 65 (61.9) | |
Hyperintensity | 40 (38.1) |
Data are number (%) of patients unless specified otherwise. *Data are number (%) of lesions out of a total number of 105 lesions, †Six lesions were pathologically confirmed as viable HCC, but degree of necrosis was not reported in pathologic report. AFp = alpha-fetoprotein, DEB = drug-eluting beads, HCC = hepatocellular carcinoma, LI-RADS = Liver Imaging Reporting and Data System, PEA = percutaneous ethanol ablation, RFA = radiofrequency ablation, TACE = transarterial chemoembolization, TARE = transarterial radioembolization, TIV = tumor-in-vein, T1-WI = T1-weighted imaging