Table 3. Comparison of Diagnostic Performance of LR-TR in Ordinary Arterial-Phase and Arterial Subtraction Images for Predicting Viable HCC.
Sensitivity (%) | P | Specificity (%) | P | Accuracy (%) | |||
---|---|---|---|---|---|---|---|
Total | |||||||
LR-TR viable | 0.002* | > 0.999† | |||||
Ordinary arterial-phase images | 63.0 (50.9–74.0) [46/73] | 93.8 (79.2–99.2) [30/32] | 72.4 (62.8–80.7) [76/105] | ||||
Arterial subtraction images | 76.7 (65.4–85.8) [56/73] | 90.6 (75.0–98.0) [29/32] | 81.0 (72.1–88.0) [85/105] | ||||
LR-TR viable + equivocal | 0.006‡ | 0.125§ | |||||
Ordinary arterial-phase images | 69.9 (58.0–80.1) [51/73] | 87.5 (71.0–96.5) [28/32] | 75.2 (65.9–83.1) [79/105] | ||||
Arterial subtraction images | 83.6 (73.4–94.9) [61/73] | 75.0 (56.6–88.5) [24/32] | 81.0 (72.1–88.0) [85/105] | ||||
TACE | |||||||
LR-TR viable | 0.031* | > 0.999† | |||||
Ordinary arterial-phase images | 67.4 (51.5–80.9) [29/43] | 90.0 (68.3–98.8) [18/20] | 74.6 (62.1–84.7) [47/63] | ||||
Arterial subtraction images | 81.4 (66.6–91.6) [35/43] | 85.0 (62.1–96.8) [17/20] | 82.5 (70.9–91.0) [52/63] | ||||
LR-TR viable + equivocal | 0.219‡ | 0.250§ | |||||
Ordinary arterial-phase images | 79.1 (64.0–90.0) [34/43] | 85.0 (62.1–96.8) [17/20] | 81.0 (69.1–89.8) [51/63] | ||||
Arterial subtraction images | 88.4 (74.9–96.1) [38/43] | 70.0 (45.7–88.1) [14/20] | 82.5 (70.9–91.0) [52/63] |
Data in parentheses are 95% confidence intervals, and data in brackets are number of lesions. *Comparison of sensitivity between ordinary arterial-phase image and arterial subtraction image when LR-TR viable was regarded as viable HCC, †Comparison of specificity between ordinary arterial-phase image and arterial subtraction image when LR-TR viable was regarded as viable HCC, ‡Comparison of sensitivity between ordinary arterial-phase image and arterial subtraction image when both LR-TR viable and equivocal were regarded as viable HCC, §Comparison of specificity between ordinary arterial-phase image and arterial subtraction image when both LR-TR viable and equivocal were regarded as viable HCC. HCC = hepatocellular carcinoma, LR-TR = Liver Imaging Reporting and Data System treatment response, TACE = transarterial chemoembolization