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. 2021 May 20;22(8):1289–1299. doi: 10.3348/kjr.2020.1394

Table 4. Characteristics of 19 Lesions with Discordant APHE* between Ordinary Arterial-Phase Images and Arterial Subtraction Images.

Characteristics Total (n = 19)
Signal intensity on precontrast T1-weighted images
Iso- or hypointensity 8 (42.1)
Hyperintensity 11 (57.9)
Pretreatment LI-RADS category
LI-RADS 4 4 (21.1)
LI-RADS 5 14 (73.6)
LI-RADS TIV 1 (5.3)
Pathological viability
Viable 18 (94.7)
Nonviable 1 (5.3)
Grade of viable HCC
Edmondson-Steiner grade 2 11 (63.1)
Edmondson-Steiner grade 3 6 (31.6)
Edmondson-Steiner grade 4 1 (5.3)
Mean size, mm (range) 14.5 (5–49)
< 10 5 (26.3)
10–20 10 (52.5)
> 20 4 (21.2)
Change of LR-TR category
LR-TR nonviable to viable 9 (47.4)
LR-TR equivocal to viable 2 (10.5)
Not changed 8 (42.1)

Data are number (%) of lesions unless specified otherwise.

*Lesions not seen as APHE on ordinary arterial phase images but seen as APHE on arterial subtraction images, Change in LR-TR category when arterial subtraction images were used. APHE = arterial phase hyperenhancement, HCC = hepatocellular carcinoma, LI-RADS = Liver Imaging Reporting and Data System, LR-TR = LI-RADS treatment response, TIV = tumor-in-vein